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Recent global statistics reveal that over 1 billion individuals are affected by obesity, including approximately 880 million adults and 159 million children and adolescents as of 2022 [4]

Our findings indicate that glucose metabolism should be followed up if long-term NAD-interventions are needed

Indeed, a search at (as of, Sep 14), employing cardiovascular disease and GLP-1 as keywords, returns 112 records comprising 42% completed, 39% recruiting, 8% not yet recruiting, 6% active, but not yet recruiting, 4% terminated, and 1% withdraw studies

These effects lead to a significant amount of weight loss in the first few months, with more gradual effects observed in the long term